Invention for Dental enamel compositions containing anti-inflammatory agents

Invented by Vivekananda Ramana, Joel Douglas, Amazon Technologies Inc

Dental enamel compositions containing anti-inflammatory agents are becoming increasingly popular in the market. These compositions are designed to provide relief to patients suffering from dental problems such as gum inflammation, tooth sensitivity, and other related issues. The market for these products is growing rapidly due to the increasing awareness among people about the importance of maintaining good oral health.

The dental enamel compositions containing anti-inflammatory agents are formulated using a variety of ingredients such as fluoride, calcium, and other minerals. These ingredients help to strengthen the enamel and prevent tooth decay. The anti-inflammatory agents used in these compositions include ibuprofen, aspirin, and other non-steroidal anti-inflammatory drugs (NSAIDs). These agents help to reduce inflammation and pain in the gums and teeth.

The market for dental enamel compositions containing anti-inflammatory agents is driven by several factors. One of the main factors is the increasing prevalence of dental problems such as gum disease, tooth decay, and sensitivity. These problems are caused by various factors such as poor oral hygiene, unhealthy diet, and smoking. The use of dental enamel compositions containing anti-inflammatory agents can help to alleviate these problems and promote good oral health.

Another factor driving the market for these products is the increasing demand for cosmetic dentistry. Many people are opting for cosmetic dental procedures such as teeth whitening, veneers, and implants. These procedures can cause sensitivity and inflammation in the teeth and gums. The use of dental enamel compositions containing anti-inflammatory agents can help to reduce these problems and promote faster healing.

The market for dental enamel compositions containing anti-inflammatory agents is also driven by the increasing availability of these products. Many dental care companies are now offering these products as part of their dental care packages. These products are also available over-the-counter in pharmacies and drug stores. This makes it easier for people to access these products and use them as part of their daily oral care routine.

In conclusion, the market for dental enamel compositions containing anti-inflammatory agents is growing rapidly due to the increasing awareness among people about the importance of maintaining good oral health. These products are formulated using a variety of ingredients that help to strengthen the enamel and prevent tooth decay. The anti-inflammatory agents used in these compositions help to reduce inflammation and pain in the gums and teeth. The market for these products is driven by several factors such as the increasing prevalence of dental problems, the demand for cosmetic dentistry, and the increasing availability of these products.

The Amazon Technologies Inc invention works as follows

Provided is a method and composition relating to a more specific dental composition to prepare the dentin of the damaged tooth before it is repaired.” Dental compositions can include a bioactive and non-aqueous solvent that includes an alcohol, anti-inflammatory, and anti-pain reliver.

Background for Dental enamel compositions containing anti-inflammatory agents

1. Field of the Invention

Dental amalgams, composite resins and porcelain can all be used to restore damaged or decayed tooth structure. A sequential application of a dental adhesive to the affected tooth structure is one method. Pretreatment is often necessary to strengthen the bonding between the adhesive and the tooth structure. The bonding process can include, for example, three steps. (1) An inorganic or an organic acid is used to remove any surface contaminants and partially demineralize dentin matrix. (2) A monomer is used to penetrate the remaining collagen-rich network. (3) Finally, an adhesive resin is applied. To bond to a dental composite resin, the adhesive resin must be cured. Tooth enamel protects against hot, cold and sticky items. Tooth enamel can become worn down and cause tooth decay. This exposes dentin and sensitive nerves within the pulp, making the tooth yellow. With age, enamel can become less strong. Enamel loss can also be caused by a high-sugar diet or acidity and/or history of acid reflux disease.

U.S. Pat. Application 200901977221 is herein incorporated as a reference and describes dental bonding solution. Application 20050142077 is herein incorporated as a reference and describes the use antimicrobial ceramic glass ceramic in dental care.

But, bioglass is a glass that has a bioactive, and sometimes antimicrobial, effect. This is what An Introduction to Bioceramics, World Scientific Publ., describes. (Hensch and Wilson, 1993). This type of bioglass is distinguished by the formation in aqueous media of hydroxylapatite layer. The applications DE-A-19932 238 and DE-A-19932 239 describe heavy metal-free alkali and alkaline Earth silicate glasses with antimicrobial properties. These documents are herein incorporated as reference in their entirety.

U.S. Patent. “A glass powder that contains 40-60 weight-percent SiO2, 5–30 weight-percent N2O, 10-35 Weight-Percent CaO, and zero-12 weight-percent Os is known.” No. No. 5,676,720, herein incorporated by reference. A glass ceramic made from this glass type of composition is also known. U.S. Pat. does not provide any information on the crystal phase. No. 5,676,720.

U.S. Pat. No. No. The crystallites are 13 m in size. Ceramization is done using tempering steps to nucleate and crystallize. It is mechanical properties, such as K1c, that are the focus. The crystal phase component ranges between 34 and 60% volume-percent. U.S. Pat. No. The 5,981,412 herein, incorporated by reference and in its entirety, only describes a phase of crystalline crystals that are a high temperature phase and only occur under the conditions specified in this document. “An application in the dental care field is not described.

The use bioactive glasses for toothpaste or gels is described in WO97/27148. Herein incorporated by reference in its entirety. U.S. Pat. reveals that there are inorganic non-metallic substances that contain calcium or phosphorus, and can lead to tooth remineralization by appropriate ion donors. Nos. Nos. 5,427/768 and 5,208 167 are herein incorporated as a reference in its entirety.

All of the above-cited publications and patents are herein incorporated as if they were individually and specifically indicated to be incorporated. They are also incorporated herein to disclose and discuss the methods and/or materials with which the publications are connected.

The prior art is not able to solve the problems associated with enamel and dentin reconstruction, inflammation, infection, and slow assimilation bioglass into dentin structures. These problems can be solved by the instant invention.

None of these references mentions the application of bioactive to the exposed dentin that has lost its enamel and caused it to yellow. Bioactive glass can be used to reduce the effects of staining as well as enhance light reflection. This will make the tooth appear whiter than the natural enamel.

But, bioglass is a glass that has a bioactive, and sometimes antimicrobial, effect. This is what An Introduction to Bioceramics, World Scientific Publ., describes. (Hensch and Wilson, 1993). This type of bioglass is distinguished by the formation in aqueous media of hydroxylapatite layer. The applications DE-A-19932 238 and DE-A-19932 239 describe heavy metal-free alkali and alkaline Earth silicate glasses with antimicrobial properties. These documents are herein incorporated as reference in their entirety.

U.S. Patents describe a glass powder consisting of SiO2 (40-60%), Na2O (5-30%), CaO (10-35%), and P2O5 (0-12%). No. The entire 5,676,720 is incorporated herein by reference, and a glass ceramic made from this type of glass composition is also known. U.S. Pat. does not provide any information on the crystal phase. No. 5,676,720.

U.S. Pat. No. No. The crystallites are 13 m in size. Ceramization is done using tempering steps to nucleation, crystallization and other processes. It is mechanical properties, such as K1c, that are the focus. The crystal phase component ranges between 34 and 60% volume-percent. U.S. Pat. No. The 5,981,412 herein, incorporated by a reference in its entirety, only describes a phase crystalline that is a phase of high temperature and that can only be formed under the conditions specified in this document. No application is described in the dental care field. U.S. Pat. U.S. Patent. “Application 20050142077 is incorporated herein by reference and describes the use antimicrobial glass ceramics in dental care.

The use bioactive glasses for toothpaste or gels is described in WO97/27148. Herein incorporated by reference in its entirety. U.S. Pat. reveals that there are inorganic non-metallic substances that contain calcium or phosphorus, and can lead to tooth remineralization by appropriate ion donors. Nos. Nos. 5,427/768 and 5,268,167 are herein incorporated by reference in their entirety. U.S. Patent Application 2009/019722 describes a method for bonding dental resin composites using a dental bonding solution. It is herein incorporated as reference in its entirety.

The glasses mentioned above are not intended to be used in the field of dental care or oral hygiene. They can only be used to enhance the whiteness perception of teeth. All the patents and publications cited above are herein incorporated as if they were each individually and explicitly indicated to be incorporated. They are also incorporated herein to describe and disclose the methods and/or materials that are related to the publications.

The instant invention solves peroxide problems by creating a dental bonding solution from bioactive glass and a suitable solvent. This is the first dental bonding technique that doesn’t use excessive bleaching or contain a high concentration of hydrogen peroxide.

The instant invention provides a way to alleviate the pain and discomfort that is associated with the process for repairing and bonding the dentin. It also offers a method to reduce discomfort and pain, reduce inflammation and aid in bone resorption after bone loss.

The disclosure provides compositions and methods relating to dental bondingslurrys useful for bonding dental resin composites. Enamel is the first line of defense for teeth against heat, cold, sticky and abrasive objects. Enamel wears away, which can lead to tooth decay. It exposes the dentin, sensitive nerves, and pulp, and makes the tooth look yellow. The enamel can weaken with age, a sugary or acidic diet, and/or an acid reflux history. Dentin hypersensitivity can also be observed in patients with periodontitis after treatment. The invention is focused on the dentinal tubeule. This is one of the small tubes or canals within the dentin. These tubules cause dentin hypersensitivity. Dentin tubules are located between the pulp cavity and the enamel. They contain odontoblastic processes, nerve filaments and other odontoblastic structures. In addition to occluding the dentin tubule with a micro-mechanical bond the invention discloses a means to increase the strength of the hydroxyapatite on surface of the tooth enamel and increase the fluidity flow of the slurry/gel into the dentin to create a much stronger bond and prevent microleakage/sensitivity. In the presence of calcium and/or phosphate in aqueous solution, it is well known that bioglass can form apatite. This helps to prevent micro-leakage and further reduce sensitivity. The time it takes for the calcium-phosphate apatite bond to form is a factor in the patient’s acceptance of the treatment.

The bioglass, when combined with calcium and phosphate in aqueous solution, can form apatite. This will further reduce sensitivity, prevent micro-leakage and enhance the appearance of the enamel structure. The process can cause pain to the patient, and it is necessary to find a way to reduce the pain. The primary therapeutic ingredients of the invention are a combination natural products that reduce inflammation and pain, aspirin or acetylsalicylic acids (ASA), which is a well-known anti-inflammatory and a pain reliever. Natural products are Neem, Punica Granatum and Menta species. Clove oil, Cannabidiol oil (CBD), Boswellia, and chlorotoxin, as well as other pain and inflammation agents, are included. “By adding these treatment agents into the suspension of the invention, the result is a minimization of discomfort and pain associated with the exposed and damaged dentin as well as the process of dental bonding and repair of the dentin.

The leaf extract of Neem or Nimba is used to treat gum disease (gingivitis), eliminate bacteria, and prevent plaque in the mouth.

Punica granatum is one of the oldest edible fruits and has a long tradition as a medical fruit. Punica granatum is a preventive and a therapeutic aid for inflammation periodontal diseases.

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